Diversity in modern heart failure trials: Where are we, and where are we going Article

Full Text via DOI: 10.1016/j.ijcard.2021.12.018 Web of Science: 000790546000022

Cited authors

  • Anaba U, Ishola A, Alabre A, Bui A, Prince M, Okafor H, Kola-Kehinde O, Joseph JJ, Mitchell D, Odei BC, Uzendu A, Williams KP, Capers Q, Addison D

Abstract

  • Over the last three decades, increased attention has been given to the representation of historically underrep-resented groups within the landscape of pivotal clinical trials. However, recent events (i.e., coronavirus pandemic) have laid bare the potential continuation of historic inequities in available clinical trials and studies aimed at the care of broad patient populations. Anecdotally, cardiovascular disease (CVD) has not been immune to these disparities. Within this review, we examine and discuss recent landmark CVD trials, with a specific focus on the representation of Blacks within several critically foundational heart failure clinical trials tied to contemporary treatment strategies and drug approvals. We also discuss solutions for inequities within the landscape of cardiovascular trials. Building a more diverse clinical trial workforce coupled with intentional ef-forts to increase clinical trial diversity will advance equity in cardiovascular care.

Publication date

  • 2022

Published in

International Standard Serial Number (ISSN)

  • 0167-5273

Number of pages

  • 7

Start page

  • 95

End page

  • 101

Volume

  • 348