The failure of gene-centrism Article

Full Text via DOI: 10.1017/S0140525X22002436 Web of Science: 001066650000001

Cited authors

  • Archer E, Lavie CJ


  • "Challenging the utility of polygenic scores for social science" is a compelling but limited critique. Phenotypic development is sensitive to both initial conditions and all subsequent states - from conception to senescence. Thus, gene-centric analyses are misleading (and often meaningless) because gene products are transformed, and their phenotypic 'effects' combined and attenuated with successive propagations from molecular and cellular contexts to organismal and social environments.

Publication date

  • 2023

Published in

International Standard Serial Number (ISSN)

  • 0140-525X

Number of pages

  • 66


  • 46