Physical Activity and Cause-Specific Cardiovascular Mortality Among People With and Without Cardiovascular Disease: A Cohort Study of 0.6 Million US Adults Article

Full Text via DOI: 10.1016/j.mayocp.2023.05.028 Web of Science: 001222480600001

Cited authors

  • Cabanas-Sánchez V, Duarte MA Jr, Lavie CJ, Celis-Morales C, Rodríguez-Artalejo F, Martínez-Gómez D

Abstract

  • Objective: To assess the association of physical activity (PA) with causespeci fi c cardiovascular disease (CVD) mortality among people with preexisting CVD and to analyze the relationship of PA with CVDrelated mortality in people without CVD as well as the association of PA with nonspeci fi c CVD mortality in both populations. Participants and Methods: Of the total participants in the 1997 through 2018 US National Health Interview Survey waves, 87,959 adults with CVD and 527,185 without CVD were included. Leisuretime PA was self -reported; based on frequency and duration, minutes per week in PA were calculated and subsequently classi fi ed into: (1) none: 0 min/wk, (2) insuf fi cient: 1 to 149.9 min/wk, (3) recommended: 150 to 300 min/wk, and (4) additional: more than 300 min/wk. Mortality data were obtained through link to records from the National Death Index. Statistical analyses were performed with Cox regression adjusted for potential confounders. Results: During a mean follow-up of 8.5 years, 12,893 participants with CVD, 9943 with coronary heart disease (CHD), and 843 with stroke died of CVD mortality, diseases of heart mortality, and cerebrovascular mortality, respectively. In fully adjusted models, compared with no PA, insuf fi cient, recommended, and additional PA were associated with 25.9%, 37.1%, and 42.0% lower risk of diseases of heart mortality among people with prior CHD, respectively. Among people with stroke, recommended and additional PA was related to 30.7% and 59.3% lower risk of cerebrovascular mortality, respectively. The protective effect of PA on causespeci fi c CVD mortality was greater in people with CVD than in those without prior CVD. Moreover, PA was more markedly inversely associated with causespeci fi c CVD mortality than with nonspeci fi c CVD mortality in people with CVD. Conclusion: Physical activity was strongly associated with lower risk of CVD-, CHD-, and strokerelated mortality among people with a history of these speci fi c diseases. Health care professionals should emphasize the importance of a physically active lifestyle in patients with CVD.

Authors

Publication date

  • 2024

Published in

International Standard Serial Number (ISSN)

  • 0025-6196

Number of pages

  • 14

Start page

  • 564

End page

  • 577

Volume

  • 99

Issue

  • 4