Harris, William; Moreno, Mauricio A.; Moore, Brian
This chapter examines the risk factors and clinical approach to regional management of aggressive skin cancer of the head and neck. Initially, the chapter touches on the epidemiology, patient evaluation, and role of imaging in head and neck cutaneous cancer. As the chapter progresses, the workup and management of aggressive cutaneous lesions is discussed, including the role of sentinel lymph node biopsy and the technique involved. Management of the N0 neck is also discussed as well as a comprehensive overview of posterolateral neck dissection technique and indications. Finally, the current recommendations on adjuvant therapy and the treatment of systemic disease are explored.