Use of alpha(2)-Agonists in Neuroanesthesia: An Overview Article

PMID: 21603337 Web of Science: 000420219500016

Cited authors

  • Farag, Ehab; Argalious, Maged; Sessler, Daniel I.; Kurz, Andrea; Ebrahim, Zeyd Y.; Schubert, Armin


  • alpha(2)-Agonists are a novel class of drugs with mechanisms of action that differ from other commonly used anesthetic drugs. They have neuroprotective, cardioprotective, and sedative effects. These unique characteristics make them potentially useful during neuroanesthesia and intensive care. We review the effects of dexmedetomidine on cerebral blood flow and cerebral metabolism, along with recent advances in using alpha(2)-agonists in neuroanesthesia and neurointensive care.

Publication date

  • 2011

Published in

International Standard Serial Number (ISSN)

  • 1524-5012

Start page

  • 57

End page

  • 69


  • 11


  • 1