Clinical Implications of Left Atrial Enlargement: A Review Article

PMID: 21603443 Web of Science: 000420201400004

Cited authors

  • Patel, Dharmendrakumar A.; Lavie, Carl J.; Milani, Richard V.; Shah, Sangeeta; Gilliland, Yvonne


  • Echocardiographically determined left atrial (LA) size has been shown to be a significant predictor of cardiovascular (CV) outcomes. We review the physiology and echocardiographic assessment of LA size and functions and describe the pathophysiologic determinants and clinical implications of LA enlargement. However, despite strong evidence, standardized LA size assessment and generalized applicability of its clinical implications to patient care have yet to be determined. Nevertheless, current findings suggest that echocardiographically determined LA size may become an important clinical risk identifier in preclinical CV disease and should be assessed as a part of routine comprehensive echocardiographic evaluation.

Publication date

  • 2009

Published in

International Standard Serial Number (ISSN)

  • 1524-5012

Start page

  • 191

End page

  • 196


  • 9


  • 4