Emerging diuretics for the treatment of heart failure Article

Full Text via DOI: 10.1517/14728210902721230 PMID: 19196235 Web of Science: 000264685900012

Cited authors

  • Sedghi, Yabiz; Gaddam, Krishna K.; Ventura, Hector O.


  • Heart failure continues to be a major global concern. Despite greater understanding of the 'maladaptive' mechanisms that contribute to its development and progression, morbidity and mortality from heart failure remain high. Existing treatment modalities have been hampered by the development of electrolyte abnormalities, diuretic resistance and the cardiorenal syndrome. This review focuses on the pharmacological properties and clinical data of therapeutic agents under investigation that target vasopressin and adenosine receptors for the treatment of patients with heart failure.

Publication date

  • 2009

Published in


International Standard Serial Number (ISSN)

  • 1472-8214

Start page

  • 195

End page

  • 204


  • 14


  • 1