Epidemiology, evaluation, and management of conduction disturbances after transcatheter aortic valve replacement Article

Full Text via DOI: 10.1016/j.pcad.2021.06.004 Web of Science: 000679973300006

Cited authors

  • Aymond JD, Benn F, Williams CM, Bernard ML, Hiltbold AE, Khatib S, Polin GM, Rogers PA, Soto JDT, Ramee SR, Parrino PE, Falterman JB, Al-Khatib SM, Morin DP


  • Aortic stenosis is the most common valvulopathy requiring replacement by means of the surgical or transcatheter approach. Transcatheter aortic valve replacement (TAVR) has quickly become a viable and often preferred treatment strategy compared to surgical aortic valve replacement. However, transcatheter heart valve system deployment not infrequently injures the specialized electrical system of the heart, leading to new conduction disorders including high-grade atrioventricular block and complete heart block (CHB) necessitating permanent pacemaker implantation (PPI), which may lead to deleterious effects on cardiac function and patient outcomes. Additional conduction disturbances (e.g., new-onset persistent left bundle branch block, PR/QRS prolongation, and transient CHB) currently lack clearly defined management algorithms leading to variable strategies among institutions. This article outlines the current understanding of the pathophysiology, patient and procedural risk factors, means for further risk stratification and monitoring of patients without a clear indication for PPI, our institutional approach, and future directions in the management and evaluation of post-TAVR conduction disturbances. (c) 2021 Elsevier Inc. All rights reserved.

Publication date

  • 2021

Published in

International Standard Serial Number (ISSN)

  • 0033-0620

Number of pages

  • 9

Start page

  • 37

End page

  • 45


  • 66