Muneer MS, Todnem N, Gopal N, Marenco-Hillembrand L, Barakat E, Mbabuike N, Brown BL, Miller DA, Freeman WD, Gupta V, Tawk RG
Objective: The Pipeline-Embolization-Device (PED) has been used increasingly for intracranial-aneurysms. Despite the high-patency-rate of jailed branches following PED deployment, little is known about changes in these vessels size. This study measured change in size after PED.& nbsp;Methods: This retrospective-study screened a database of 183-consecutive-patients treated with PED (07/2011-07/2017) across inclusion criteria. We included patients in whom the ophthalmic artery (OA) and/or the pos-terior communicating artery (PComA) were jailed by the PED. MRA was used to calculate change in cross-sectional-area (CSA) of these vessels. 29 patients who had MRA before and after treatment were included in the study. The CSA was measured automatically using Syngo (R).via-software at fixed points along the analyzed vessels. After exclusion of low-quality and software non-capturable MRA-images, 16 OA and 23 PComA were included in the final analysis. Statistical Package for Social Sciences was used for analysis.& nbsp;Results: The mean CSA of PComA, P1-segement of posteriror-cerebral-artery (P1-PCA), and OA was 3.3 +/- 1.3, 4.1 +/- 1.2, and 3.2 +/- 0.9 mm(2) at baseline and 1.9 +/- 1.4, 4.3 +/- 1.2, and 3.1 +/- 0.7 mm(2) at follow-up, respectively. The average follow-up was approximately 26 months. While the decrease in CSA of PComA was statistically signif-icant, the increase in P1-PCA CSA was not. The change in OA CSA was not statistically significant.& nbsp;Conclusion: Jailing PComA with a PED resulted in a statistically significant decrease in PComA CSA and a statistically non-significant increase in ipsilateral P1 CSA. No statistically significant change in the CSA of OA was noted. Changes might be due to a balance between flow demand through the jailed ostium and presence of collateral flow.