David Margolin, MD, FACS, FASCRS
- Research, Southshore Region
- 1514 Jefferson Hwy, New Orleans, LA, 70121
For additional information or to make an appointment, click here.
Overview
Overview
- Dr. Margolin earned his medical degree from the Medical College of Ohio in Toledo and completed his internship and residency at Case Western Reserve University in Cleveland, Ohio. He completed his fellowship in colon and rectal surgery at Ochsner. Dr. Margolin is board certified in general surgery and colon and rectal surgery and has been on staff at Ochsner since the beginning of 2003. Dr. Margolin is listed in Best Doctors in America. He serves as Director of Colon and Rectal Surgery Research. His professional interests include laparoscopic colon and rectal surgery, inflammatory bowel disease, complex anorectal conditions and incontinence.
Publications
Selected publications
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2021Caveolin-1-driven membrane remodelling regulates hnRNPK-mediated exosomal microRNA sorting in cancer. Clinical and Translational Medicine. 11.
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2020ANTI-CD3 AND ANTI-CD28 BEAD-BASED STIMULATION FOR IN VITRO GENERATION OF HUMAN T CELLS FOR USE IN A PATIENT-DERIVED ORTHOTOPIC MOUSE MODEL. Journal of Investigative Medicine. 68:634-634.
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2020GAMMA AMINOBUTYRIC ACID A RECEPTOR PI SUBUNIT EXPRESSION AS A PROGNOSTIC BIOMARKER FOR COLON CANCER PATIENTS. Journal of Investigative Medicine. 68:646-646.
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2020Modified Frailty Index Predicts Postoperative Outcomes in Patients Undergoing Radical Pelvic Surgery. American Surgeon. 86:95-103.
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2020TARGETABLE MICRORNAS IN THE COLORECTAL CANCER EXTRACELLULAR MICROENVIRONMENT. Journal of Investigative Medicine. 68:638-639.
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2019Anastomotic Leak Rate Is Doubled in Patients Diagnosed with Clostridium difficile Infection after Colectomy: A Retrospective Review Using the NSQIP Database. Journal of The American College of Surgeons. 229:S51-S51.
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2019EXAMINING THE EFFECT OF A CYCLIC PEPTIDE CXCR4 ANTAGONIST, LY2510924, IN AN ORTHOTOPIC XENOGRAFT MICE MODEL ON COLORECTAL CANCER TUMOR GROWTH AND METASTASIS. Journal of Investigative Medicine. 67:592-592.
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2019EXAMINING THE EFFECT OF A CYCLIC PEPTIDE CXCR4 ANTAGONIST, LY2510924, IN AN ORTHOTOPIC XENOGRAFT MICE MODEL ON COLORECTAL CANCER TUMOR GROWTH AND METASTASIS. Journal of Investigative Medicine. 67:567-567.
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2019Elucidating the Molecular Biomarkers Associated with Increase Responsiveness to a Cyclic Peptide CXCR4 Antagonist, LY2510924, in an Orthotopic Xenograft Mice Model on Colorectal Cancer Tumor Growth and Metastasis. Journal of The American College of Surgeons. 229:S60-S60.
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2019Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis. Journal of Visualized Experiments.
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2019QUANTIFICATION OF THE INFLUENCE OF LYMPH NODE STROMAL MICROENVIRONMENT ON THE PROTEIN EXPRESSION AND REGULATION OF RENAL CELL CARCINOMA PROGRESSION. Journal of Investigative Medicine. 67:591-591.
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2019The Role of Bowel Preparation in Colorectal Surgery Results of the 2012-2015 ACS-NSQIP Data. Annals of Surgery. 269:671-677.
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2018A Novel Wound Retractor Combining Continuous Irrigation and Barrier Protection Reduces Incisional Contamination in Colorectal Surgery. World Journal of Surgery. 42:3000-3007.
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2018An Optimal Orthotopic Mouse Model for Human Colorectal Cancer Primary Tumor Growth and Spontaneous Metastasis. Diseases of the Colon and Rectum. 61:698-705.
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2018Clopidogrel bisulfate (Plavix) does not increase bleeding complications in patients undergoing rubber band ligation for symptomatic hemorrhoids. Journal of Surgical Research. 229:230-233.
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2018Evaluating the Inhibitory Effects of LY2510924, a Cyclic Peptide CXCR4 Antagonist, in Human Colon Cancer Metastasis Using an Orthotopic Xenograft Model. Journal of The American College of Surgeons. 227:S64-S65.
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2018LYMPH NODE STROMAL CELLS SUPPORT TUMOUR GOWTH VIA BONE MARROW DERIVED EPITHELIAL CELLS IN HUMAN COLORECTAL CANCER. Journal of Investigative Medicine. 66:576-577.
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2018Morbidity Following Coloanal Anastomosis: A Comparison of Colonic J-Pouch vs Straight Anastomosis. Diseases of the Colon and Rectum. 61:156-161.
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2018Novel Safe Withanolide Inhibits Orthotopic and Metastatic Colorectal Cancer Growth In Vivo Through Wnt Blockade. Annals of Surgical Oncology. 25:S169-S170.
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2017THE EFFECTS OF RAB13 DERIVED FROM LYMPH NODE STROMAL CELL EXTRACELLULAR VESICLES ON THE PATHOGENESIS OF HUMAN COLORECTAL CANCER. Journal of Investigative Medicine. 65:590-591.
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2017The emerging Roles of extracellular vesicles As Communication vehicles within the Tumor Microenvironment and Beyond. Frontiers in Endocrinology. 8.
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2017
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2016Advances in colonoscopy and screening for colon cancer. Seminars in Colon and Rectal Surgery. 27:181-186.
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2016Comparison of 30-Day Postoperative Outcomes after Laparoscopic vs Robotic Colectomy. Journal of The American College of Surgeons. 223:369-373.
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2016Current State of Colorectal Surgery Training: A Survey of Program Directors, Current and Recently Matched Colorectal Residents, and Recent Colorectal Graduates. Diseases of the Colon and Rectum. 59:140-147.
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2016EMERGING ROLES OF MICROVESICLES DELIVERED BY LYMPH NODE STROMAL CELLS IN THE PATHOGENESIS OF HUMAN COLORECTAL CANCER. Journal of Investigative Medicine. 64:657-658.
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2016Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage. Journal of Gastrointestinal Surgery. 20:2035-2051.
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2016THE ROLE OF CANCER STEM CELLS IN COLORECTAL CANCER METASTASIS. Journal of Investigative Medicine. 64:658-658.
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2016UNDERSTANDING THE ROLE OF LYMPH NODE STROMAL MICROENVIRONMENT IN ESOPHAGEAL ADENOCARCINOMA BY USING A PATIENT-DERIVED ORTHOTOPIC MODEL. Journal of Investigative Medicine. 64:704-705.
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2015Benefits of a Multimodal Regimen for Postsurgical Pain Management in Colorectal Surgery. The Ochsner Journal. 15:408-412.
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2015Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes The ACOSOG Z6051 Randomized Clinical Trial. Journal of the American Medical Association. 314:1346-1355.
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2015Non-physician endoscopists: A systematic review. World Journal of Gastroenterology. 21:5056-5071.
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2015Perfusion Assessment in Laparoscopic Left-Sided/Anterior Resection (PILLAR II): A Multi-Institutional Study. Journal of The American College of Surgeons. 220:82-U118.
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2015The Role of Transanal Surgery in the Management of T1 Rectal Cancers. Journal of Gastrointestinal Surgery. 19:1704-1712.
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2014A systematic review of the performance and cost-efficiency of nurse and non-physician endoscopists. Journal of Gastroenterology and Hepatology. 29:30-30.
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2014Current status: new technologies for the treatment of patients with fecal incontinence. Surgical Endoscopy. 28:2277-2301.
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2014STROMAL CELLS PROVIDE SUPPORTVE NICHE FOR TUMORIGENESIS AND METASTASIS IN ESOPHAGEAL ADENOCARCINOMA. Journal of Investigative Medicine. 62:528-528.
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2013CD 133(+) and CXCR4(+) colon cancer cells as a marker for lymph node metastasis. Journal of Surgical Research. 185:113-118.
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2013Restorative Proctocolectomy: The Current Ochsner Experience. The Ochsner Journal. 13:512-516.
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2013Social Media and the Surgeon. Clinics in Colon and Rectal Surgery. 26:36-38.
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2013Targeting Cancer Stem Cells Reply. The Ochsner Journal. 13:277-277.
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2013Timing of Colonoscopy After Resection for Colorectal Cancer: Are We Looking Too Soon?. Diseases of the Colon and Rectum. 56:1233-1236.
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2012Intramural Colonic Splenosis: A Rare Case of Lower Gastrointestinal Bleeding. Journal of Gastrointestinal Surgery. 16:1632-1634.
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2010Infection Rates in a Large Investigational Trial of Sacral Nerve Stimulation for Fecal Incontinence. Journal of Gastrointestinal Surgery. 14:1081-1088.
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2010Sacral Nerve Stimulation for Fecal Incontinence Results of a 120-Patient Prospective Multicenter Study. Annals of Surgery. 251:441-449.
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2010Variations in Perioperative Steroid Management among Surgical Subspecialists. American Surgeon. 76:1363-1367.
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2008New Options for the Treatment of Fecal Incontinence. The Ochsner Journal. 8:18-24.
Visualizations
Research areas
- Biochemistry & Molecular Biology
- Cell Biology
- Endocrinology & Metabolism
- Gastroenterology & Hepatology
- General & Internal Medicine
- Genetics & Heredity
- Immunology
- Infectious Diseases
- Life Sciences & Biomedicine - Other Topics
- Oncology
- Research & Experimental Medicine
- Science & Technology - Other Topics
- Surgery